CX3CL1/Fractalkine Products
CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.
189 results for "CX3CL1/Fractalkine" in Products
189 results for "CX3CL1/Fractalkine" in Products
CX3CL1/Fractalkine Products
CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.
| Sensitivity: | 0.072 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine, Human Milk) |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Sensitivity: | 0.32 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.62 - 40 ng/mL (Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma, Heparin Plasma) |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Assay Range: | 0.625 - 20 ng/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #126315 |
| Applications: | WB, Neut |
| Source: | NS0 |
| Accession #: | P78423 |
| Applications: | BA, BA |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #81513 |
| Applications: | WB, IHC |
| Source: | Sf 21 (baculovirus) |
| Accession #: | O35188 |
| Applications: | BA, BA |
| Source: | E. coli |
| Accession #: | O35188 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | Q6I9S9 |
| Applications: | BA, BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #81506 |
| Applications: | CyTOF-ready, ICFlow, Neut |
| Assay Range: | 0.391 - 25 ng/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #51637 |
| Applications: | CyTOF-ready, ICFlow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #126315 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #51637 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #51637 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #51637 |
| Applications: | WB |
| Source: | E. coli |
| Accession #: | O55145 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Source: | Sf 21 (baculovirus) |
| Accession #: | O55145 |
| Applications: | BA |
| Assay Range: | 195 - 12,500 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #51637 |
| Applications: | ICFlow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #126315 |
| Applications: | Flow |
