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FGF-21 Products

FGF-21 (Fibroblast Growth Factor 21) is a member of an FGF subfamily that also includes FGF-19 and FGF-23. FGF-19 subfamily members lack a heparin binding domain, enabling them to freely circulate as endocrine factors and diffuse within tissues. FGF-21 signals through Klotho beta in complex with FGF receptors. It regulates cellular metabolism including glucose uptake in adipocytes and cellular sensitivity to insulin. It is basally expressed in the pancreas, thymus, liver, and adipose tissue and is upregulated in liver, muscle, and fat in obesity and diabetes. FGF-21 also plays a role in cell survival and proliferation, mesenchymal stem cell differentiation, circadian rhythm, and controlling reproductive capacity.

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99 results for "FGF-21" in Products

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99 results for "FGF-21" in Products

FGF-21 Products

FGF-21 (Fibroblast Growth Factor 21) is a member of an FGF subfamily that also includes FGF-19 and FGF-23. FGF-19 subfamily members lack a heparin binding domain, enabling them to freely circulate as endocrine factors and diffuse within tissues. FGF-21 signals through Klotho beta in complex with FGF receptors. It regulates cellular metabolism including glucose uptake in adipocytes and cellular sensitivity to insulin. It is basally expressed in the pancreas, thymus, liver, and adipose tissue and is upregulated in liver, muscle, and fat in obesity and diabetes. FGF-21 also plays a role in cell survival and proliferation, mesenchymal stem cell differentiation, circadian rhythm, and controlling reproductive capacity.

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Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Applications: Simple Plex

Build your own multi-plex biomarker immunoassay panel for Ella™. Highly precise and reproducible. Choose from more than 250 fully validated target analytes.

Simple Plex Human FGF-21 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: WB
Reactivity: Mouse

Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies

Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies

Applications: WB, ELISA
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: Ctrl, Simple Plex

Control for use with Human FGF-21 Simple Plex Cartridge Kit

Applications: WB
Reactivity: Human, Mouse
Applications: CyTOF-ready, ICC, ICFlow
Reactivity: Human
Applications: Neut
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: IHC, WB, ICC/IF
Reactivity: Human
Applications: IHC, WB, ICC/IF, Flow
Reactivity: Human
Applications: ELISA
Reactivity: Human

Control for use with Mouse/Rat FGF-21 Simple Plex Assay Cartridge Kit

Applications: WB
Reactivity: Mouse
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