FGF-21 Products
FGF-21 (Fibroblast Growth Factor 21) is a member of an FGF subfamily that also includes FGF-19 and FGF-23. FGF-19 subfamily members lack a heparin binding domain, enabling them to freely circulate as endocrine factors and diffuse within tissues. FGF-21 signals through Klotho beta in complex with FGF receptors. It regulates cellular metabolism including glucose uptake in adipocytes and cellular sensitivity to insulin. It is basally expressed in the pancreas, thymus, liver, and adipose tissue and is upregulated in liver, muscle, and fat in obesity and diabetes. FGF-21 also plays a role in cell survival and proliferation, mesenchymal stem cell differentiation, circadian rhythm, and controlling reproductive capacity.
88 results for "FGF-21" in Products
88 results for "FGF-21" in Products
FGF-21 Products
FGF-21 (Fibroblast Growth Factor 21) is a member of an FGF subfamily that also includes FGF-19 and FGF-23. FGF-19 subfamily members lack a heparin binding domain, enabling them to freely circulate as endocrine factors and diffuse within tissues. FGF-21 signals through Klotho beta in complex with FGF receptors. It regulates cellular metabolism including glucose uptake in adipocytes and cellular sensitivity to insulin. It is basally expressed in the pancreas, thymus, liver, and adipose tissue and is upregulated in liver, muscle, and fat in obesity and diabetes. FGF-21 also plays a role in cell survival and proliferation, mesenchymal stem cell differentiation, circadian rhythm, and controlling reproductive capacity.
| Sensitivity: | 13.4 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Sensitivity: | 8.69 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Source: | E. coli |
| Accession #: | Q9NSA1 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Source: | NS0 |
| Accession #: | Q9JJN1 |
| Applications: | BA |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #315914 |
| Applications: | WB |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #315901 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #461804 |
| Applications: | CyTOF-ready, ICC, ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Goat IgG2b Monoclonal Clone #40020A |
| Applications: | Neut |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: FGF-21 Antibody [NBP1-31368]](https://resources.bio-techne.com/images/products/FGF-21-Antibody-Western-Blot-NBP1-31368-img0008.jpg "Western Blot: FGF-21 Antibody [NBP1-31368]")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #OTI2F10 |
| Applications: | IHC, WB, ICC/IF, Flow |
![Western Blot: FGF-21 Antibody (OTI2F10) [NBP2-00645]](https://resources.bio-techne.com/images/products/FGF21-Antibody-2F10-Western-Blot-NBP2-00645-img0002.jpg "Western Blot: FGF-21 Antibody (OTI2F10) [NBP2-00645]")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #461804 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #461804 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #461804 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #461804 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #461804 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #461804 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #461804 |
| Applications: | ICFlow |
| Applications: | ELISA |
| Applications: | WB |
![Western Blot: FGF-21 Overexpression Lysate [NBL1-10695]](https://resources.bio-techne.com/images/products/FGF21-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-10695-img0002.jpg "Western Blot: FGF-21 Overexpression Lysate [NBL1-10695]")