GDNF: Proteins and Enzymes
GDNF (Glial Cell Line-derived Neurotrophic Factor) is a secreted protein that promotes the survival of motoneurons, midbrain dopaminergic neurons, Purkinje cells, and sympathetic neurons. It is produced by Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes, and skeletal muscle cells. GDNF binding to GFR alpha 1 induces the recruitment of Ret, NCAM-1/CD56, various integrins, Syndecan-3, or N-Cadherin. GDNF-based therapies show promise in several neurodegenerative disorders, particularly Parkinson’s disease.
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8 results for "GDNF Proteins and Enzymes" in Products
8 results for "GDNF Proteins and Enzymes" in Products
GDNF: Proteins and Enzymes
GDNF (Glial Cell Line-derived Neurotrophic Factor) is a secreted protein that promotes the survival of motoneurons, midbrain dopaminergic neurons, Purkinje cells, and sympathetic neurons. It is produced by Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes, and skeletal muscle cells. GDNF binding to GFR alpha 1 induces the recruitment of Ret, NCAM-1/CD56, various integrins, Syndecan-3, or N-Cadherin. GDNF-based therapies show promise in several neurodegenerative disorders, particularly Parkinson’s disease.
Products:
Analyzed by SEC-MALS
| Source: | NS0 |
| Accession #: | P39905 |
| Applications: | BA, Bind |
| Source: | NS0 |
| Accession #: | P39905.1 |
| Applications: | BA, Bind |
| Source: | Sf 21 (baculovirus) |
| Accession #: | Q07731 |
| Applications: | BA, Bind |
| Source: | E. coli |
| Accession #: | P39905.1 |
| Applications: | BA |
| Applications: | AC |
| Applications: | Bioactivity, PAGE |
![SDS-PAGE: Recombinant Human GDNF Protein [NBP2-34888]](https://resources.bio-techne.com/images/products/Human-GDNF-Protein-SDS-Page-NBP2-34888-img0001.jpg "SDS-PAGE: Recombinant Human GDNF Protein [NBP2-34888]")
| Applications: | Bioactivity |
| Applications: | Bioactivity, PAGE |