GLI-1 Products
GLI family proteins are zinc finger transcription factors best known for regulating the expression of gene targets of Hedgehog (Hh) signaling. They share homology with the Drosophila Ci protein, which serves as a mediator of Hh responses in the fly. GLI-1 is a member of the Krupple family of zinc finger proteins. GLI-1 is activated by the sonic hedgehog pathway and influences transcription of a variety of target genes by binding to the consensus site 5CGGGTGGTC3. GLI- activation leads to cellular proliferation and anti-apoptotic activities based on target genes activated.
91 results for "GLI-1" in Products
91 results for "GLI-1" in Products
GLI-1 Products
GLI family proteins are zinc finger transcription factors best known for regulating the expression of gene targets of Hedgehog (Hh) signaling. They share homology with the Drosophila Ci protein, which serves as a mediator of Hh responses in the fly. GLI-1 is a member of the Krupple family of zinc finger proteins. GLI-1 is activated by the sonic hedgehog pathway and influences transcription of a variety of target genes by binding to the consensus site 5CGGGTGGTC3. GLI- activation leads to cellular proliferation and anti-apoptotic activities based on target genes activated.
| Reactivity: | Human, Mouse, Canine, Porcine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
![Knockdown Validated: GLI-1 Antibody - BSA Free [NB600-600]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-Immunohistochemistry-Paraffin-NB600-600-img0005.jpg "Immunohistochemistry: GLI-1 Antibody - BSA Free [NB600-600]")
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Func, MA |
![Immunohistochemistry: GLI-1 Antibody - BSA Free [NBP1-78259]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-Immunohistochemistry-NBP1-78259-img0009.jpg "Immunohistochemistry: GLI-1 Antibody - BSA Free [NBP1-78259]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ChIP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4E2 |
| Applications: | IHC, WB, ICC/IF, KD |
![Western Blot: GLI-1 Antibody (OTI4E2) [NBP2-45872]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-4E2-Western-Blot-NBP2-45872-img0011.jpg "Western Blot: GLI-1 Antibody (OTI4E2) [NBP2-45872]")
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JF09-08 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: GLI-1 Antibody (JF09-08) [NBP2-66867]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-JF09-08-Western-Blot-NBP2-66867-img0007.jpg "Western Blot: GLI-1 Antibody (JF09-08) [NBP2-66867]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2B Monoclonal Clone #CL12193 |
| Applications: | IHC, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #CL12192 |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: GLI-1 Antibody [NBP3-21211] -](https://resources.bio-techne.com/images/products/nbp3-21211_mouse-gli-1-mab-cl12192-45202315534353.jpg "Immunohistochemistry-Paraffin: GLI-1 Antibody [NBP3-21211] -")
GLI antagonist; inhibits Hedgehog (Hh) signaling
| Chemical Name: | 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine |
| Purity: | ≥98% (HPLC) |
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL12191 |
| Applications: | WB, ICC/IF |
![Immunocytochemistry/Immunofluorescence: GLI-1 Antibody [NBP3-21210] -](https://resources.bio-techne.com/images/products/nbp3-21210_mouse-gli-1-mab-cl12191-45202315531347.jpg "Immunocytochemistry/Immunofluorescence: GLI-1 Antibody [NBP3-21210] -")
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: GLI-1 Antibody [NBP2-68877]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-68877-img0001.jpg "Immunocytochemistry/ Immunofluorescence: GLI-1 Antibody [NBP2-68877]")
| Applications: | AC |
| Applications: | WB |
![Western Blot: GLI-1 Overexpression Lysate [NBL1-11109]](https://resources.bio-techne.com/images/products/Gli1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11109-img0002.jpg "Western Blot: GLI-1 Overexpression Lysate [NBL1-11109]")
| Applications: | ELISA |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4E2 |
| Applications: | IHC, WB, KD |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Func |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4E2 |
| Applications: | IHC, WB, KD |
| Reactivity: | Human, Mouse, Canine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Func |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Func |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4E2 |
| Applications: | IHC, WB, ICC/IF, KD |