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ICAM-1/CD54 Products

ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1  (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.

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397 results for "ICAM-1/CD54" in Products

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397 results for "ICAM-1/CD54" in Products

ICAM-1/CD54 Products

ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1  (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.

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Applications: WB, Flow, IP, AdBlk, ICC
Reactivity: Human
Applications: WB, IHC, AdBlk
Reactivity: Mouse
Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: Simple Plex

Simple Plex Human ICAM-1/CD54 assay kit for use on Ella instrument. Contains cartridge, sample diluent 000303, and wash buffer.

Applications: WB, IHC, AdBlk
Reactivity: Rat
Applications: Flow
Reactivity: Human
Applications: WB, IHC, ICC, KO
Reactivity: Human
Applications: IHC, WB, ICC/IF, Flow, Func, B/N, MS, Simple Western
Reactivity: Human, Mouse, Rat
Applications: WB, AdBlk, ICC, KO
Reactivity: Human
Applications: WB, ICC
Reactivity: Human

Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies

Applications: WB, IHC
Reactivity: Mouse
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