mGluR8 Products
The Group III metabotropic glutamate receptors include mGluR4, 6, 7 and 8. These 7-transmembrane glycoproteins are negatively coupled to adenylate cyclase and expressed presynaptically throughout the brain. MGluR8 shows pronounced expression in the dentate gyrus and CA3 regions of the hippocampus, and is thought to play a role in memory formation.
15 results for "mGluR8" in Products
15 results for "mGluR8" in Products
mGluR8 Products
The Group III metabotropic glutamate receptors include mGluR4, 6, 7 and 8. These 7-transmembrane glycoproteins are negatively coupled to adenylate cyclase and expressed presynaptically throughout the brain. MGluR8 shows pronounced expression in the dentate gyrus and CA3 regions of the hippocampus, and is thought to play a role in memory formation.
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #476410 |
| Applications: | WB, IHC |
| Source: | CHO |
| Accession #: | O00222-1 |
| Applications: | WB |
![Western Blot: mGluR8 Overexpression Lysate [NBP2-11380]](https://resources.bio-techne.com/images/products/metabotropic-Glutamate-Receptor-8-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-11380-img0001.jpg "Western Blot: mGluR8 Overexpression Lysate [NBP2-11380]")
| Applications: | WB |
![Western Blot: mGluR8 Overexpression Lysate [NBL1-11352]](https://resources.bio-techne.com/images/products/metabotropic-Glutamate-Receptor-8-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11352-img0002.jpg "Western Blot: mGluR8 Overexpression Lysate [NBL1-11352]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #4A7 |
| Applications: | WB, ELISA |
Selective group III mGlu agonist
| Chemical Name: | L-(+)-2-Amino-4-phosphonobutyric acid |
| Purity: | ≥99% (HPLC) |
Potent and highly selective group II mGlu agonist
| Chemical Name: | (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid |
| Purity: | ≥98% (HPLC) |
Potent group III mGlu antagonist
| Chemical Name: | (RS)-α-Cyclopropyl-4-phosphonophenylglycine |
| Purity: | ≥98% (HPLC) |
Potent and selective mGlu8a agonist
| Alternate Names: | UBP 1109 |
| Chemical Name: | (S)-3,4-Dicarboxyphenylglycine |
| Purity: | ≥98% (HPLC) |
Positive allosteric modulator of mGlu7 and mGlu8 receptors; also NK1 antagonist; brain penetrant
| Chemical Name: | 3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine |
| Purity: | ≥98% (HPLC) |
Selective positive allosteric modulator of group III mGlu receptors
| Alternate Names: | ML 396 |
| Chemical Name: | N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
Positive allosteric modulator of group I mGlu receptors
| Chemical Name: | (9H-Xanthen-9-ylcarbonyl)-carbamic acid butyl ester |
| Purity: | ≥99% (HPLC) |
Active metabolite of oxcarbazepine (Cat. No. 3864)
| Alternate Names: | GP 47779 |
| Chemical Name: | 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide |
| Purity: | ≥98% (HPLC) |
