TIMP-2 Products
TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.
136 results for "TIMP-2" in Products
136 results for "TIMP-2" in Products
TIMP-2 Products
TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIMP2/8193R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIMP2/8193R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat, Bovine, Zebrafish, +2 More |
| Details: | Rabbit IgG Monoclonal Clone #TIMP2/2488R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIMP2/8193R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #TIMP2/2044 |
| Applications: | IHC, ELISA, MA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #TIMP2/8193R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #TIMP2/2044 |
| Applications: | IHC, ELISA, MA |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat, Bovine, Zebrafish, +2 More |
| Details: | Rabbit IgG Monoclonal Clone #TIMP2/2488R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #TIMP2/2044 |
| Applications: | IHC, ELISA, MA |
| Sensitivity: | 0.064 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine) |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Dual ISH-IHC, KO, Neut |
| Source: | CHO |
| Accession #: | P16035 |
| Applications: | InhibAct |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #89025 |
| Applications: | WB, IHC |
| Source: | NS0 |
| Accession #: | NP_035724 |
| Applications: | EnzAct |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1A6 |
| Applications: | IHC, WB, ICC/IF, Flow |
![Western Blot: TIMP-2 Antibody (OTI1A6) [NBP2-01573]](https://resources.bio-techne.com/images/products/TIMP2-Antibody-1A6-Western-Blot-NBP2-01573-img0003.jpg "Western Blot: TIMP-2 Antibody (OTI1A6) [NBP2-01573]")
| Source: | CHO |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #127711 |
| Applications: | KO |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #F27 P3 A4 |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: TIMP-2 Antibody (F27 P3 A4) [NB100-74552]](https://resources.bio-techne.com/images/products/TIMP-2-Antibody-F27-P3-A4-Immunocytochemistry-Immunofluorescence-NB100-74552-img0006.jpg "Immunocytochemistry/ Immunofluorescence: TIMP-2 Antibody (F27 P3 A4) [NB100-74552]")
| Assay Range: | 7.81 - 500 pg/mL |
| Applications: | ELISA |
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human TIMP-2 His Protein [NBP2-22869]](https://resources.bio-techne.com/images/products/Recombinant-Human-TIMP-2-Protein-SDS-Page-NBP2-22869-img0002.jpg "SDS-PAGE: Recombinant Human TIMP-2 His Protein [NBP2-22869]")
For use with catalog number DTM200
| Applications: | ELISA, Ctrl |
| Reactivity: | Human, Mouse, Zebrafish, Porcine, Rabbit, +1 More |
| Details: | Mouse IgG2A Monoclonal Clone #3A4 |
| Applications: | IHC, WB, ELISA |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #3A4 |
| Applications: | IHC, WB, B/N |