Actin Products
The Actin protein, a component of the eukaryotic cytoskeleton, is highly conserved between multiple species. Actin is a globular protein of approximately 42kDa. Levels of the Actin protein may vary between different cell types, but are consistent within a given cell type. For this reason, Actin protein levels are often considered a 'house-keeper', an internal control for protein loading.
The actin network represents an essential component of the cell cytoskeleton, which is made up of microfilaments composed of linear assemblies of actin molecules. Actin assembly is known to be important for the remodeling of cell shape during cell motility, cell division and morphogenesis. The biological functions of actin occur in concert with a large number of Actin binding proteins, including cofilin, actin depolymerization factor (ADF), myosins, and many more.
Actin molecules accumulate as Hirano bodies, in neurons of patients with Alzheimer's disease, Creutzfeldt-Jakob disease, and other neurodegenerative diseases. Hirano bodies are intracellular aggregates of actin and actin-associated proteins.
105 results for "Actin" in Products
105 results for "Actin" in Products
Actin Products
The Actin protein, a component of the eukaryotic cytoskeleton, is highly conserved between multiple species. Actin is a globular protein of approximately 42kDa. Levels of the Actin protein may vary between different cell types, but are consistent within a given cell type. For this reason, Actin protein levels are often considered a 'house-keeper', an internal control for protein loading.
The actin network represents an essential component of the cell cytoskeleton, which is made up of microfilaments composed of linear assemblies of actin molecules. Actin assembly is known to be important for the remodeling of cell shape during cell motility, cell division and morphogenesis. The biological functions of actin occur in concert with a large number of Actin binding proteins, including cofilin, actin depolymerization factor (ADF), myosins, and many more.
Actin molecules accumulate as Hirano bodies, in neurons of patients with Alzheimer's disease, Creutzfeldt-Jakob disease, and other neurodegenerative diseases. Hirano bodies are intracellular aggregates of actin and actin-associated proteins.
| Reactivity: | Human, Mouse, Rat, Bovine, Zebrafish, +12 More |
| Details: | Mouse IgM Kappa Monoclonal Clone #mAbGEa |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +1 More |
![Flow (Intracellular): Actin Antibody (mAbGEa) [NB100-74340]](https://resources.bio-techne.com/images/products/Actin-Antibody-mAbGEa-Flow-Intracellular-NB100-74340-img0020.jpg "Flow (Intracellular): Actin Antibody (mAbGEa) [NB100-74340]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #3U6B8 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Actin Antibody (3U6B8) [NBP3-16100]](https://resources.bio-techne.com/images/products/Actin-Antibody-3U6B8-Western-Blot-NBP3-16100-img0006.jpg "Western Blot: Actin Antibody (3U6B8) [NBP3-16100]")
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #25E3 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Actin Antibody [NBP2-98923]](https://resources.bio-techne.com/images/products/Actin-Antibody-Western-Blot-NBP2-98923-img0006.jpg "Western Blot: Actin Antibody [NBP2-98923]")
| Reactivity: | Human, Rat, Porcine, Rabbit, Goat |
| Details: | Mouse IgG1 Monoclonal Clone #3B3 |
| Applications: | IHC, WB, ELISA |
![Immunohistochemistry-Paraffin: Actin Antibody (3B3) - BSA Free [NBP1-97723]](https://resources.bio-techne.com/images/products/Actin-Alpha-1-Skeletal-Muscle-Antibody-3B3-Immunohistochemistry-Paraffin-NBP1-97723-img0005.jpg "Immunohistochemistry-Paraffin: Actin Antibody (3B3) - BSA Free [NBP1-97723]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S05-4F6 |
| Applications: | IHC, WB |
![Western Blot: Actin Antibody (S05-4F6) [NBP3-19993]](https://resources.bio-techne.com/images/products/Actin-Antibody-S05-4F6-Western-Blot-NBP3-19993-img0002.jpg "Western Blot: Actin Antibody (S05-4F6) [NBP3-19993]")
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #4C1 |
| Applications: | IHC, ELISA, Flow |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Actin Antibody [NBP2-15256]](https://resources.bio-techne.com/images/products/Actin-Alpha-1-Skeletal-Muscle-Antibody-Western-Blot-NBP2-15256-img0002.jpg "Western Blot: Actin Antibody [NBP2-15256]")
| Reactivity: | Plant |
| Details: | Mouse IgG1 Monoclonal Clone #9Y9L6 |
| Applications: | WB |
![Western Blot: Actin Antibody (9Y9L6) [NBP3-16885]](https://resources.bio-techne.com/images/products/Actin-Antibody-9Y9L6-Western-Blot-NBP3-16885-img0001.jpg "Western Blot: Actin Antibody (9Y9L6) [NBP3-16885]")
| Applications: | WB, ELISA, MA, AP |
![SDS-PAGE: Recombinant Human Actin GST (N-Term) Protein [H00000058-P01]](https://resources.bio-techne.com/images/products/Recombinant-Human-Actin-Alpha-1-Skeletal-Muscle-Protein-SDS-Page-H00000058-P01-img0002.jpg "SDS-PAGE: Recombinant Human Actin GST (N-Term) Protein [H00000058-P01]")
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #ACTA1/360 |
| Applications: | IHC, WB, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #ACTA1/360 |
| Applications: | IHC, WB, ICC/IF, Flow |
| Reactivity: | Human, Rat, Porcine, Rabbit, Goat |
| Details: | Mouse IgG1 Monoclonal Clone #3B3 |
| Applications: | IHC, WB, ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #ACTA1/360 |
| Applications: | IHC, WB, ICC/IF, Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #ACTA1/360 |
| Applications: | IHC, WB, ICC/IF, Flow |
Disrupts actin filament function
| Alternate Names: | Zygosporin A |
| Chemical Name: | (7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione |
| Purity: | ≥95% (HPLC) |
Stabilizes F-actin; promotes actin polymerization
| Chemical Name: | Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl] |
| Purity: | ≥97% (HPLC) |
Green-fluorescent cytoskeleton stain. Binds and labels F-actin. Used for: F-actin staining. Application: fluorescent microscopy, immunofluorescence (IHC, ICC)
| Chemical Name: | 7-[(4R)-N5-[[(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]-4-hydroxy-4-methyl-L-ornithine]phalloidin |
| Purity: | ≥90% (HPLC) |
Inhibitor of actin assembly and polymerization
| Chemical Name: | 4-[(1R,4Z,8E,10Z,12S,15R, 17R)-17-Hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl)-2-thiazolidinone |
| Purity: | ≥95% (HPLC) |
Red-orange fluorescent cytoskeleton stain. Binds and labels F-actin. Used for: F-actin staining. Application: fluorescent microscopy, immunofluorescence (IHC, ICC)
| Chemical Name: | 7-[(4R)-5-[[[[4-[3,6-Bis(dimethylamino)xanthylium-9-yl]-3-carboxyphenyl]amino]thioxomethyl]amino]-4-hydroxy-L-leucine]phalloidin |
| Purity: | ≥90% (HPLC) |
Inhibitor of actin polymerization
| Chemical Name: | (4R)-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-2-thiazolidinone |
| Purity: | ≥95% (HPLC) |
