Histone Acetyltransferase Inhibitors Products
Histone Acetyltransferases (HATs) are also known as Lysine Aceyltransferases or KATs. These are domains found in a diverse range of enzymes, and they are responsible for catalyzing the acetylation of lysine residues. This post-translational modification involves the transfer of an acetyl group from acetyl CoA to form ε-N-acetyl lysine.
11 results for "Histone Acetyltransferase Inhibitors" in Products
11 results for "Histone Acetyltransferase Inhibitors" in Products
Histone Acetyltransferase Inhibitors Products
Histone Acetyltransferases (HATs) are also known as Lysine Aceyltransferases or KATs. These are domains found in a diverse range of enzymes, and they are responsible for catalyzing the acetylation of lysine residues. This post-translational modification involves the transfer of an acetyl group from acetyl CoA to form ε-N-acetyl lysine.
Inhibitor of KAT5 (Tip60)
| Chemical Name: | 5-(1,2-Thiazol-5-yldisulfanyl)-1,2-thiazole |
Potent and selective p300/CBP inhibitor; orally bioavailable
| Chemical Name: | (1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2',4'-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5'-oxazolidine]-3'-acetamide |
| Purity: | ≥98% (HPLC) |
Lysine acetyltransferase HBO1 (KAT7) inhibitor
| Chemical Name: | N'-(4-Fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)-3-hydroxybenzenesulfonohydrazide |
| Purity: | ≥98% (HPLC) |
Potent p300/CBP inhibitor
| Chemical Name: | (1'S,3'R)-3'-Fluoro-N-[(4-fluorophenyl)methyl]-2',3'-dihydro-5'-[1-[2-(methylamino)-2-oxoethyl]-1H-pyrazol-4-yl]-2,5-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[imidazolidine-4,1'-[1H]indene]-1-acetamide |
| Purity: | ≥98% |
Potent and selective KAT6A and KAT6B inhibitor
| Chemical Name: | N'-(4-Fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)benzenesulfonohydrazide |
| Purity: | ≥98% |
Noncompetitive PCAF/p300 inhibitor
| Chemical Name: | 2-Hydroxy-6-pentadecylbenzoic acid |
| Purity: | ≥97% (HPLC) |
Reversible and non-competitive CBP/p300 inhibitor
| Chemical Name: | 5-[(4-Hydroxy-2,6-dimethylphenyl)methylene]-1,3-bis(phenylmethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione |
| Purity: | ≥98% (HPLC) |
High affinity KAT6A (MOZ) competitive inhibitor
| Chemical Name: | 2-Fluoro-N'-(3-fluoro-5-(pyridin-2-yl)benzoyl)benzenesulfonohydrazide |
| Purity: | ≥98% |
Steroid receptor coactivator 3 (SRC-3) inhibitor
| Chemical Name: | 1-(2-Pyridinyl)ethanone 2-(1-methyl-1H-benzimidazol-2-yl)hydrazone hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective EP300 Degrader (PROTAC®)
| Chemical Name: | 12-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)-N-((R)-3'-(2-((4-fluorobenzyl)((S)-1,1,1-trifluoropropan-2-yl)amino)-2-oxoethyl)-2',4'-dioxo-2,3-dihydrospiro[indene-1,5'-oxazolidin]-5-yl)dodecanamide |
| Purity: | ≥98% (HPLC) |
Negative control for iP300w (Cat. No. 7270)
| Chemical Name: | (1'R,3'S)-3'-Fluoro-N-[(4-fluorophenyl)methyl]-2',3'-dihydro-5'-[1-[2-(methylamino)-2-oxoethyl]-1H-pyrazol-4-yl]-2,5-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[imidazolidine-4,1'-[1H]indene]-1-acetamide |
| Purity: | ≥98% |
