IL-1 beta/IL-1F2 Products
IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.
107 results for "IL-1 beta/IL-1F2" in Products
107 results for "IL-1 beta/IL-1F2" in Products
IL-1 beta/IL-1F2 Products
IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.
Assay Range: | 15.6 - 1,000 pg/mL |
Applications: | ELISA |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, Simple Western, IHC, ICC, Neut |
Source: | E. coli |
Accession #: | NP_032387 |
Applications: | BA |
Reactivity: | Human, Mouse, Rat, Canine, Monkey, +5 More |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, ELISA, Flow, +4 More |
Reactivity: | Mouse |
Details: | Rat IgG1 Monoclonal Clone #30311 |
Applications: | Neut |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, Simple Western, Neut |
Reactivity: | Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, ELISA, Flow, +3 More |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Mouse |
Details: | Hamster IgG Monoclonal Clone #B122 |
Applications: | WB, IP, Neut |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #166926 |
Applications: | WB |
Recombinant Monoclonal Antibody.
Reactivity: | Mouse |
Details: | Rat IgG1 Monoclonal Clone #30311R |
Applications: | ICC, Neut |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #A7F7-R |
Applications: | IHC, WB, ELISA |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #001 |
Applications: | ELISA |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #001 |
Applications: | ELISA |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #001 |
Applications: | ELISA |
Reactivity: | Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF, Flow, +3 More |
Reactivity: | Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF, Flow, +3 More |
Reactivity: | Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF, Flow, +3 More |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #001 |
Applications: | ELISA |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #001 |
Applications: | ELISA |