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IL-10 Products

IL-10 (Interleukin-10) functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.

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265 results for "IL-10" in Products

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265 results for "IL-10" in Products

IL-10 Products

IL-10 (Interleukin-10) functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.

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2 plate pack size has been discontinued.

This product is in the process of discontinuation.

Applications: BA

Analyzed by SEC-MALS.

Applications: BA

Animal Free

Applications: WB, Neut
Reactivity: Mouse

Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies

Applications: WB, ICC, Neut
Reactivity: Mouse, Rat

Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Applications: WB, Simple Western, IHC, Neut
Reactivity: Human
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