IL-10 Products
IL-10 (Interleukin-10) functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.
242 results for "IL-10" in Products
242 results for "IL-10" in Products
IL-10 Products
IL-10 (Interleukin-10) functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.
| Sensitivity: | 3.9 pg/mL |
| Applications: | ELISA |
| Assay Range: | 7.8 - 500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
2 plate pack size has been discontinued.
| Sensitivity: | 5.22 pg/mL |
| Applications: | ELISA |
| Assay Range: | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
This product is in the process of discontinuation.
| Applications: | Simple Plex |
Analyzed by SEC-MALS.
| Source: | E. coli |
| Accession #: | P22301.1 |
| Applications: | BA |
Animal Free
| Source: | E. coli |
| Accession #: | P22301.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_034678 |
| Applications: | BA |
| Sensitivity: | 10 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma) |
| Sensitivity: | 0.17 pg/mL |
| Applications: | ELISA |
| Assay Range: | 0.78 - 50 pg/mL (Serum, EDTA Plasma, Citrate Plasma) |
Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #JES052A5 |
| Applications: | WB, Neut |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications: | ELISA |
Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications: | ELISA |
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #23738 |
| Applications: | WB, Simple Western, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, Neut |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications: | ELISA |
| Sensitivity: | 3.8 pg/mL |
| Applications: | ELISA |
| Assay Range: | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Build your own multi-plex biomarker immunoassay panel for Ella™. Highly precise and reproducible. Choose from more than 250 fully validated target analytes.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.