5-HT1A Products
5-HT1A is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin(1A) receptors, including 5-HT1A, belong to the family of G protein-coupled receptors and are implicated in the generation and modulation of various cognitive, behavioral and developmental functions. A relationship between 5-HT1A receptors and serotonin transporter (5-HTT) is also suggested by the pathophysiology of depression and the mechanism of action of antidepressants.
29 results for "5-HT1A" in Products
29 results for "5-HT1A" in Products
5-HT1A Products
5-HT1A is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin(1A) receptors, including 5-HT1A, belong to the family of G protein-coupled receptors and are implicated in the generation and modulation of various cognitive, behavioral and developmental functions. A relationship between 5-HT1A receptors and serotonin transporter (5-HTT) is also suggested by the pathophysiology of depression and the mechanism of action of antidepressants.
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
Purity: | ≥98% |
Endogenous 5-HT receptor agonist
Alternate Names: | 5-Hydroxytryptamine,5-HT |
Chemical Name: | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
Purity: | ≥98% (HPLC) |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, Simple Western |
CCR2b chemokine receptor antagonist
Chemical Name: | 1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride |
Purity: | ≥99% (HPLC) |
Potent 5-HT1A antagonist; also D4 agonist
Chemical Name: | N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate |
Purity: | ≥99% (HPLC) |
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
Chemical Name: | 4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate |
Purity: | ≥98% (HPLC) |
Potent and selective 5-HT1A antagonist
Chemical Name: | (S)-N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide dihydrochloride |
Purity: | ≥99% (HPLC) |
5-HT1A antagonist
Chemical Name: | 1-(2-Methoxyphenyl)-4-(4-phthalimidobutyl)piperazine hydrobromide |
Purity: | ≥98% (HPLC) |
Selective, high affinity 5-HT1A antagonist
Chemical Name: | (3R)-3-(Dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide hydrochloride |
Purity: | ≥98% (HPLC) |
5-HT1A, 5-HT1B and 5-HT1D agonist
Chemical Name: | 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate |
Purity: | ≥99% |
Selective 5-HT1A partial agonist
Chemical Name: | (3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione hydrochloride |
Purity: | ≥98% |
Highly potent D2-like antagonist; also 5-HT1A agonist
Chemical Name: | cis-5-Chloro-2-methoxy-4-(methylamino)-N-[2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]benzamide |
Purity: | ≥99% |
Selective 5-HT1A agonist
Chemical Name: | 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3(2H)-one-1,1-dioxide |
Purity: | ≥99% |
5-HT1A and 5-HT1B agonist
Chemical Name: | 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate |
Purity: | ≥99% |
Potent 5-HT1A partial agonist and SSRI; antidepressant
Chemical Name: | 5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamide hydrochloride |
Purity: | ≥98% |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
Chemical Name: | 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone |
Purity: | ≥99% (HPLC) |
Applications: | ELISA |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB |
Applications: | WB, ELISA, MA, AP |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit Polyclonal |
Applications: | WB, ELISA, IP |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit Polyclonal |
Applications: | IHC, WB, ELISA |
Potent and selective 5-HT2B and 5-HT2C antagonist; orally active
Chemical Name: | 3,5-Dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide hydrochloride |
Purity: | ≥99% (HPLC) |
α partial agonist; also D2-like partial agonist and 5-HT antagonist
Chemical Name: | 9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione mesylate |
Purity: | ≥98% (HPLC) |