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IL-1 beta/IL-1F2 Products

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

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118 results for "IL-1 beta/IL-1F2" in Products

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118 results for "IL-1 beta/IL-1F2" in Products

IL-1 beta/IL-1F2 Products

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

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Applications: WB, Simple Western, IHC, ICC, Neut
Reactivity: Mouse
Applications: IHC, WB, ICC/IF, ELISA, Flow, B/N, DB, IP, MS
Reactivity: Human, Mouse, Rat, Canine, Monkey, +5 More
Applications: WB, Simple Western, IHC, Dual ISH-IHC, ICC, Neut
Reactivity: Human
Applications: WB, ICC, Neut
Reactivity: Rat
Applications: WB
Reactivity: Mouse
Applications: WB, ICC
Reactivity: Human
Applications: WB, Simple Western, Neut
Reactivity: Mouse
Applications: IHC, WB, ICC/IF, ELISA, Flow, CyTOF-ready, DB, IP
Reactivity: Mouse, Rat
Applications: IHC, WB, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: WB, IP, Neut
Reactivity: Mouse
Applications: WB
Reactivity: Porcine
Applications: WB, ICC
Reactivity: Rat
Applications: WB, ICC, Neut
Reactivity: Feline
Applications: WB, ICC, Neut
Reactivity: Human
Applications: WB, Neut
Reactivity: Porcine
Applications: WB, CyTOF-ready, ICFlow, Neut
Reactivity: Canine
Applications: WB, ICC
Reactivity: Feline
Applications: WB, ICC, Neut
Reactivity: Equine
Applications: ICFlow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: WB, Neut
Reactivity: Cotton Rat
Applications: WB, ICFlow
Reactivity: Canine
Applications: IHC, WB, ICC/IF, Flow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: ELISA
Reactivity: Mouse

Recombinant Monoclonal Antibody

Applications: WB
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: WB
Reactivity: Human

Recombinant Monoclonal Antibody

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