Nicotinic Acetylcholine R alpha 7/CHRNA7 Products
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. nAChR alpha 7/CHRNA7 forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once nAChR alpha 7/CHRNA7 binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
56 results for "Nicotinic Acetylcholine R alpha 7/CHRNA7" in Products
56 results for "Nicotinic Acetylcholine R alpha 7/CHRNA7" in Products
Nicotinic Acetylcholine R alpha 7/CHRNA7 Products
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. nAChR alpha 7/CHRNA7 forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once nAChR alpha 7/CHRNA7 binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #7F10G1 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow |
![Western Blot: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody (7F10G1)BSA Free [NBP2-61739]](https://resources.bio-techne.com/images/products/Nicotinic-Acetylcholine-R-alpha-7-CHRNA7-Antibody-7F10G1-Western-Blot-NBP2-61739-img0005.jpg "Western Blot: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody (7F10G1)BSA Free [NBP2-61739]")
| Reactivity: | Human, Canine, Monkey, Bovine, Porcine, +2 More |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Immunohistochemistry-Paraffin: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody [NBP1-52375]](https://resources.bio-techne.com/images/products/Nicotinic-Acetylcholine-R-alpha-7-CHRNA7-Antibody-Immunohistochemistry-Paraffin-NBP1-52375-img0004.jpg "Immunohistochemistry-Paraffin: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody [NBP1-52375]")
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody [NBP1-79948]](https://resources.bio-techne.com/images/products/Nicotinic-Acetylcholine-R-alpha-7-CHRNA7-Antibody-Western-Blot-NBP1-79948-img0008.jpg "Western Blot: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody [NBP1-79948]")
| Applications: | WB, ELISA, MA, AP, PAGE |
![SDS-PAGE: Recombinant Human Nicotinic Acetylcholine R alpha 7/CHRNA7 Protein [H00001139-Q01]](https://resources.bio-techne.com/images/products/Recombinant-Human-Nicotinic-Acetylcholine-R-alpha-7-CHRNA7-Protein-SDS-Page-H00001139-Q01-img0001.jpg "SDS-PAGE: Recombinant Human Nicotinic Acetylcholine R alpha 7/CHRNA7 Protein [H00001139-Q01]")
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #7F10F1 |
| Applications: | WB, ELISA, Flow |
![Western Blot: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody (7F10F1)BSA Free [NBP2-61738]](https://resources.bio-techne.com/images/products/Nicotinic-Acetylcholine-R-alpha-7-CHRNA7-Antibody-7F10F1-Western-Blot-NBP2-61738-img0004.jpg "Western Blot: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody (7F10F1)BSA Free [NBP2-61738]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody [NBP1-80092]](https://resources.bio-techne.com/images/products/Nicotinic-Acetylcholine-R-alpha-7-CHRNA7-Antibody-Western-Blot-NBP1-80092-img0002.jpg "Western Blot: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody [NBP1-80092]")
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody [NBP2-99069]](https://resources.bio-techne.com/images/products/Nicotinic-Acetylcholine-R-alpha-7-CHRNA7-Antibody-Immunohistochemistry-Paraffin-NBP2-99069-img0001.jpg "Immunohistochemistry-Paraffin: Nicotinic Acetylcholine R alpha 7/CHRNA7 Antibody [NBP2-99069]")
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
Selective α7 nAChR antagonist
| Alternate Names: | α-Bgtx,α-BuTX |
| Purity: | ≥98% (HPLC) |
Positive allosteric modulator of α7 nAChRs; also positive allosteric modulator of P2X4 receptors
| Chemical Name: | 22,23-Dihydroavermectin B1 |
| Purity: | ≥96% |
Selective α7 neuronal nAChR antagonist
| Alternate Names: | MLA |
| Chemical Name: | [1α,4(S),6β,14α,16β]-20-Ethyl-1,6,14,16-tetramethoxy-4-[[[2-(3-methyl-2,5-dioxo-1-pyrrolidinyl)benzoyl]oxy]methyl]aconitane-7,8-diol citrate |
| Purity: | ≥95% (HPLC) |
Selective α7 nAChR agonist
| Chemical Name: | N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide |
| Purity: | ≥98% |
Positive allosteric modulator of α7 nAChRs; active in vivo
| Chemical Name: | N-(5-Chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]urea |
| Purity: | ≥98% |
Selective α7 nAChR agonist
| Chemical Name: | N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,3-dihydro-1,4-benzodioxin-6-carboxamide fumarate |
| Purity: | ≥99% (HPLC) |
Positive allosteric modulator of α7 nAChRs; active in vivo
| Chemical Name: | N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea |
| Purity: | ≥99% (HPLC) |
Positive allosteric modulator of α7 nAChRs
| Chemical Name: | 4-[5-(4-Chlorophenyl)-2-methyl-3-(1-oxopropyl)-1H-pyrrol-1-yl]benzenesulfonamide |
| Purity: | ≥97% |
Allosteric potentiator of α7, α4β2 and α4β4 nAChRs
| Chemical Name: | [2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone |
| Purity: | ≥98% (HPLC) |
Broad spectrum glutamatergic antagonist
| Chemical Name: | 4-Hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% (HPLC) |
Potent and selective α7 nAChR agonist
| Chemical Name: | N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-furo[2,3-c]pyridine-5-carboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
α7 nAChR partial agonist
| Chemical Name: | 2-[2-(4-Bromophenyl)-2-oxoethyl]-1-methylpyridinium iodide |
| Purity: | ≥99% (HPLC) |
Selective α7 nAChR partial agonist
| Chemical Name: | 4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT3 antagonist; also α7 nAChR partial agonist
| Chemical Name: | (3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylic acid ester monohydrochloride |
| Purity: | ≥99% |
