PKN2 Products
Serine/Threonine Protein Kinases N1 and N2 are PKC family members that are downstream effectors of RhoA. Both promote the activation of several kinases involved in regulation of the actin cytoskeleton, cell cycle, and apoptosis. PKN1 can be activated by proteolysis, lipid interaction, or Rho G proteins. PKN2 cleavage during apoptosis generates a C-terminal fragment that inhibits PDK1 and Akt. PKN2 is also important in the intracellular replication of hepatitis C virus and Yersinia pestis.
18 results for "PKN2" in Products
18 results for "PKN2" in Products
PKN2 Products
Serine/Threonine Protein Kinases N1 and N2 are PKC family members that are downstream effectors of RhoA. Both promote the activation of several kinases involved in regulation of the actin cytoskeleton, cell cycle, and apoptosis. PKN1 can be activated by proteolysis, lipid interaction, or Rho G proteins. PKN2 cleavage during apoptosis generates a C-terminal fragment that inhibits PDK1 and Akt. PKN2 is also important in the intracellular replication of hepatitis C virus and Yersinia pestis.
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #509105 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat, Monkey, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #1D1 |
| Applications: | IHC, WB, ELISA, Flow |
![Western Blot: PKN2 Antibody (1D1)BSA Free [NBP2-37573]](https://resources.bio-techne.com/images/products/PKN2-Antibody-1D1-Western-Blot-NBP2-37573-img0003.jpg "Western Blot: PKN2 Antibody (1D1)BSA Free [NBP2-37573]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1067 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: PKN2 Antibody [NBP1-31367]](https://resources.bio-techne.com/images/products/PKN2-Antibody-Western-Blot-NBP1-31367-img0004.jpg "Western Blot: PKN2 Antibody [NBP1-31367]")
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #20A8 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1159 |
| Applications: | WB, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: PKN2 Antibody [NBP2-13766]](https://resources.bio-techne.com/images/products/PKN2-Antibody-Western-Blot-NBP2-13766-img0004.jpg "Western Blot: PKN2 Antibody [NBP2-13766]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: PKN2 Antibody [NBP2-68736]](https://resources.bio-techne.com/images/products/PKN2-Antibody-Western-Blot-NBP2-68736-img0001.jpg "Western Blot: PKN2 Antibody [NBP2-68736]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #3A7 |
| Applications: | WB, ELISA, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: PKN2 Antibody (3A7) [H00005586-M01]](https://resources.bio-techne.com/images/products/PKN2-Antibody-3A7-Immunocytochemistry-Immunofluorescence-H00005586-M01-img0004.jpg "Immunocytochemistry/ Immunofluorescence: PKN2 Antibody (3A7) [H00005586-M01]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #5O2G6 |
| Applications: | WB, ICC/IF |
![Western Blot: PKN2 Antibody (5O2G6) [NBP3-15891]](https://resources.bio-techne.com/images/products/PKN2-Antibody-5O2G6-Western-Blot-NBP3-15891-img0001.jpg "Western Blot: PKN2 Antibody (5O2G6) [NBP3-15891]")
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #11H3 |
| Applications: | WB, ELISA, Flow |
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: PKN2 Antibody [NBP1-30086]](https://resources.bio-techne.com/images/products/PKN2-Antibody-Western-Blot-NBP1-30086-img0002.jpg "Western Blot: PKN2 Antibody [NBP1-30086]")
| Applications: | WB |
![Western Blot: PKN2 Overexpression Lysate [NBP2-07651]](https://resources.bio-techne.com/images/products/PKN2-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-07651-img0001.jpg "Western Blot: PKN2 Overexpression Lysate [NBP2-07651]")
| Applications: | AC |
| Applications: | AC |
Inhibitor of cyclic nucleotide dependent- and Rho-kinases
| Alternate Names: | HA 1077 |
| Purity: | ≥98% (HPLC) |
Potent and selective PKG2 inhibitor
| Chemical Name: | 4-[4-(1H-Imidazol-1-yl)phenyl]-N-2-propyn-1-yl-2-pyrimidinamine |
| Purity: | ≥98% (HPLC) |
