PPAR gamma/NR1C3: Small Molecules and Peptides
Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a lipid-activated nuclear hormone receptor with roles in adipocyte differentiation, lipid and glucose metabolism, and modulation of immune and inflammatory reactions. PPAR gamma is the receptor for insulin-sensitizing thiazolidinediones, commonly used for the treatment of type 2 diabetes.
Products:
15 results for "PPAR gamma/NR1C3 Small Molecules and Peptides" in Products
15 results for "PPAR gamma/NR1C3 Small Molecules and Peptides" in Products
PPAR gamma/NR1C3: Small Molecules and Peptides
Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a lipid-activated nuclear hormone receptor with roles in adipocyte differentiation, lipid and glucose metabolism, and modulation of immune and inflammatory reactions. PPAR gamma is the receptor for insulin-sensitizing thiazolidinediones, commonly used for the treatment of type 2 diabetes.
Products:
Selective covalent PPARγ antagonist
| Chemical Name: | 2-Chloro-5-nitro-N-phenylbenzamide |
| Purity: | ≥98% (HPLC) |
Highly potent and selective covalent PPARγ antagonist
| Chemical Name: | 2-Chloro-5-nitro-N-4-pyridinylbenzamide |
| Purity: | ≥99% (HPLC) |
Selective PPARγ agonist; antidiabetic agent
| Alternate Names: | Rezulin |
| Chemical Name: | 5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Purity: | ≥98% (HPLC) |
Selective PPARγ antagonist; antidiabetic and antiobesity agent
| Alternate Names: | Mifobate |
| Chemical Name: | (4-Chlorophenyl)(dimethoxyphosphinyl)methyl phosphoric acid dimethyl ester |
| Purity: | ≥99% (HPLC) |
Selective PPARγ agonist. Orally active
| Chemical Name: | N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective PPARγ agonist; antidiabetic agent
| Alternate Names: | BRL 49653 |
| Chemical Name: | 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Purity: | ≥98% (HPLC) |
Selective PPARγ agonist; antidiabetic agent
| Chemical Name: | 5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride |
| Purity: | ≥99% (HPLC) |
EGFR kinase inhibitor. Also estrogen and PPARγ ligand
| Chemical Name: | 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Purity: | ≥98% (HPLC) |
Dual site PPARγ inhibitor
| Chemical Name: | 2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide |
| Purity: | ≥98% (HPLC) |
Potent and selective PPARγ agonist; antidiabetic
| Alternate Names: | R 483,BM 131258 |
| Chemical Name: | 5-[[4-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethoxy]benzo[b]thien-7-yl]methyl]-2,4-thiazolidinedione |
| Purity: | ≥98% (HPLC) |
Potent, selective PPARγ partial agonist
| Chemical Name: | 5-Chloro-1-[(4-chlorophenyl)methyl]-3-(phenylthio)-1H-indole-2-carboxylic acid |
| Purity: | ≥98% (HPLC) |
PPARγ partial agonist
| Chemical Name: | 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit
| Alternate Names: | Gleevec,CGP 57148B |
| Chemical Name: | 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate |
| Purity: | ≥98% (HPLC) |
PPARα/γ agonist
| Alternate Names: | AZ 242 |
| Chemical Name: | (S)-2-Ethoxy-3-[4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl]propanoic acid |
| Purity: | ≥98% (HPLC) |
Nrf2 signaling activator
| Chemical Name: | 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole |
| Purity: | ≥98% (HPLC) |
