Chemokine Receptor Antagonists: Small Molecules and Peptides
29 results for "Chemokine Receptor Antagonists Small Molecules and Peptides" in Products
29 results for "Chemokine Receptor Antagonists Small Molecules and Peptides" in Products
Chemokine Receptor Antagonists: Small Molecules and Peptides
Highly selective CCR2 chemokine receptor antagonist
| Chemical Name: | 6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one |
| Purity: | ≥99% (HPLC) |
CCR2b chemokine receptor antagonist
| Chemical Name: | 1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent CCR1 chemokine receptor antagonist
| Chemical Name: | 1,4-cis-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidinium iodide |
| Purity: | ≥98% (HPLC) |
Potent and selective CCR5 and CCR2 chemokine receptor antagonist
| Chemical Name: | N-[[4-[[[6,7-Dihydro-2-(4-methylphenyl)-5H-benzocyclohepten-8-yl]carbonyl]amino]phenyl]methyl]tetrahydro-N,N-dimethyl-2H-pyran-4-aminium chloride |
| Purity: | ≥98% (HPLC) |
Highly selective CXCR4 antagonist
| Alternate Names: | JM 3100,Plerixafor |
| Chemical Name: | 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride |
Selective CCR5 antagonist
| Alternate Names: | UK-427857 |
| Chemical Name: | 4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl- 5-methyl-4H-1,2,4-triazol-4-yl)- 8-azabicyclo[3.2.1]oct-8-yl]-1- phenylpropyl}cyclohexanecarboxamide |
| Purity: | ≥99% (HPLC) |
High affinity, potent CCR2 antagonist
| Chemical Name: | 2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide |
| Purity: | ≥98% (HPLC) |
CXCR3 antagonist; inhibits cell migration and metastasis
| Chemical Name: | N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide |
| Purity: | ≥98% (HPLC) |
CXCR4 antagonist; ACKR3 (CXCR7) agonist
| Purity: | ≥95% (HPLC) |
Potent and selective CCR3 antagonist
| Chemical Name: | N-(1-Naphthalenylcarbonyl)-4-nitro-L-phenylalanine methyl ester |
| Purity: | ≥99% (HPLC) |
Potent CCR4 antagonist
| Chemical Name: | 2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride |
| Purity: | ≥99% (HPLC) |
Potent and selective CXCR2 antagonist
| Chemical Name: | N-(2-Bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)urea |
| Purity: | ≥99% (HPLC) |
Potent and selective CXCR4 antagonist
| Chemical Name: | N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide |
| Purity: | ≥97% (HPLC) |
Potent CXCR2 antagonist
| Chemical Name: | N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea |
| Purity: | ≥98% (HPLC) |
Selective CCR2 antagonist
| Chemical Name: | N-[2-[[(3R)-1-[trans-4-Hydroxy-4-(6-methoxy-3-pyridinyl)cyclohexyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)-benzamide dimethanesulfonate |
| Purity: | ≥98% (HPLC) |
Potent CXCR2 antagonist
| Chemical Name: | 6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide |
| Purity: | ≥98% (HPLC) |
Potent and selective CXCR3 antagonist
| Chemical Name: | N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)benzeneacetamide |
| Purity: | ≥98% (HPLC) |
Potent CXCR4 antagonist
| Chemical Name: | N,N'-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochloride |
| Purity: | ≥99% (HPLC) |
CXCR4 antagonist; antitumor
| Purity: | ≥95% (HPLC) |
Potent CXCR2 antagonist
| Chemical Name: | 5-[[(3-Chloro-2-fluorophenyl)methyl]thio]-7-[[(1R)-2-hydroxy-1-methylethyl]amino]thiazolo[4,5-d]pyrimidin-2(3H)-one |
| Purity: | ≥98% (HPLC) |
Potent and selective CCR3 antagonist
| Chemical Name: | N-Benzoyl-4-nitroaniline ethyl ester |
| Purity: | ≥99% (HPLC) |
CX3CR1 antagonist
| Chemical Name: | 5-[3-[4-(4-Chlorophenyl)-1-piperidinyl]propyl]pyrrolo[1,2-a]quinoxalin-4(5H)-one hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective CCR4 antagonist
| Chemical Name: | 2,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
Potent and selective CCR10 antagonist
| Chemical Name: | N-[(1R)-3-(2-Cyano-1H-pyrrol-1-yl)-1-[(4-methyl-1-piperidinyl)carbonyl]propyl]-1H-indole-4-sulfonamide |
| Purity: | ≥98% (HPLC) |
Potent and selective hCXCR6 antagonist
| Chemical Name: | N-[(1R,3S,5S)-9-(2-((2-Chlorophenyl)amino)-2-exoethyl)-9-azabicyclo[3.3.1]nonan-3-yl)-3,4,5-trimethoxybenzamide |
| Purity: | ≥98% (HPLC) |
