Src Products
Src and other Src family protein tyrosine kinases are proto-oncogenes that play key roles in regulating cell growth and differentiation. Src family activity is regulated by tyrosine phosphorylation at two sites with opposing effects. Phosphorylation at Y419 of human Src up-regulates kinase activity, while phosphorylation at Y530 inactivates Src....
44 results for "Src" in Products
44 results for "Src" in Products
Src Products
Src and other Src family protein tyrosine kinases are proto-oncogenes that play key roles in regulating cell growth and differentiation. Src family activity is regulated by tyrosine phosphorylation at two sites with opposing effects. Phosphorylation at Y419 of human Src up-regulates kinase activity, while phosphorylation at Y530 inactivates Src....
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western, IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC |
Dual site Src kinase inhibitor
| Chemical Name: | 6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine |
| Purity: | ≥99% (HPLC) |
Potent and selective c-Src inhibitor
| Chemical Name: | 1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse Monoclonal Clone #5A18 |
| Applications: | IHC, WB, Simple Western |
![Western Blot: Src Antibody (5A18) [NBP1-19188]](https://resources.bio-techne.com/images/products/Src-Antibody-5A18-Western-Blot-NBP1-19188-img0004.jpg "Western Blot: Src Antibody (5A18) [NBP1-19188]")
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1246F |
| Applications: | WB, Simple Western, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Monoclonal Clone #327537 |
| Applications: | WB |
| Assay Range: | 3.91 - 250 pg/mL |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #7G6M9 |
| Applications: | WB, ELISA, ICC/IF, IP, KO |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #327554 |
| Applications: | WB, IHC |
| Source: | Sf 9 (baculovirus) |
| Accession #: | NM_005417 |
| Applications: | BA |
| Applications: | IHC, WB, Simple Western |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Src [p Tyr527] Antibody [NBP3-13245]](https://resources.bio-techne.com/images/products/Src-[p-Tyr527]-Antibody-Western-Blot-NBP3-13245-img0004.jpg "Western Blot: Src [p Tyr527] Antibody [NBP3-13245]")
| Source: | Sf 9 (baculovirus) |
| Accession #: | M11753 |
| Applications: | BA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S05-7H8 |
| Applications: | IHC, WB |
![Western Blot: Src Antibody (S05-7H8) [NBP3-20055]](https://resources.bio-techne.com/images/products/Src-Antibody-S05-7H8-Western-Blot-NBP3-20055-img0002.jpg "Western Blot: Src Antibody (S05-7H8) [NBP3-20055]")
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #21H5 |
| Applications: | WB, ELISA, ICC/IF, Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S01-6H3 |
| Applications: | WB |
![Src [p Tyr419] Antibody (S01-6H3)](https://resources.bio-techne.com/images/products/antibody/nbp3-19758_rabbit-src-p-tyr419-mab-s01-6h3-western-blot-298202312423..jpg "Western Blot-NBP3-19758-Src [p Tyr419] Antibody (S01-6H3)-")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S03-8H8 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Src [p Tyr416] Antibody [NBP3-13419]](https://resources.bio-techne.com/images/products/Src-[p-Tyr416]-Antibody-Western-Blot-NBP3-13419-img0001.jpg "Western Blot: Src [p Tyr416] Antibody [NBP3-13419]")
| Applications: | WB |
![Western Blot: Src Overexpression Lysate [NBP2-07751]](https://resources.bio-techne.com/images/products/Src-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-07751-img0001.jpg "Western Blot: Src Overexpression Lysate [NBP2-07751]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: Src Antibody [NBP2-38165]](https://resources.bio-techne.com/images/products/Src-Antibody-Western-Blot-NBP2-38165-img0009.jpg "Western Blot: Src Antibody [NBP2-38165]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Src [p Ser17] AntibodyBSA Free [NBP3-05433]](https://resources.bio-techne.com/images/products/Src-[p-Ser17]-Antibody-Western-Blot-NBP3-05433-img0001.jpg "Western Blot: Src [p Ser17] AntibodyBSA Free [NBP3-05433]")
| Applications: | AC |
| Applications: | WB |
![Western Blot: Src Overexpression Lysate [NBP2-04722]](https://resources.bio-techne.com/images/products/Src-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-04722-img0001.jpg "Western Blot: Src Overexpression Lysate [NBP2-04722]")
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable
| Alternate Names: | AZD 0530 |
| Chemical Name: | N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine |
| Purity: | ≥98% (HPLC) |
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable
| Chemical Name: | 2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide |
| Purity: | ≥98% (HPLC) |
Potent, selective Src family kinase inhibitor
| Chemical Name: | 3-(4-chlorophenyl) 1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥99% (HPLC) |
Potent, selective Src family kinase inhibitor
| Chemical Name: | 1-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% (HPLC) |
Highly potent pan-Src/Bcr-Abl inhibitor
| Alternate Names: | BMS-354825 |
| Chemical Name: | N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective Lck and Src inhibitor; also inhibits SIK
| Alternate Names: | KIN112 |
| Chemical Name: | 2,6-Dimethylphenyl-N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]carbamate |
| Purity: | ≥98% (HPLC) |
Potent Src inhibitor; also inhibits FGFR1, PDGFRβ and Wee1
| Chemical Name: | 6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one dihydrochloride |
| Purity: | ≥99% (HPLC) |
UNC119 chaperone-cargo interaction inhibitor; disrupts Src activation
| Chemical Name: | Ethyl 4-((3,4-dioxo-2-((2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)amino)cyclobut-1-en-1-yl)amino)piperidine-1-carboxylate hydrochloride |
| Purity: | ≥98% (HPLC) |
Src family kinase inhibitor; also inhibits c-Abl
| Alternate Names: | 1-NA-PP 1 |
| Chemical Name: | 1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥99% (HPLC) |
Src tyrosine kinase inhibitor
| Chemical Name: | N-(2-Chloro-5-methoxyphenyl)-6-methoxy |
| Purity: | ≥99% (HPLC) |
Dual Src-Abl inhibitor; antiproliferative
| Alternate Names: | SKI-606 |
| Chemical Name: | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile |
| Purity: | ≥99% |
Inhibitor of Src family kinases
| Chemical Name: | 7-[trans-4-(4-Methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-Pyrrolo[2,3-d]pyrimidin-4-amine trihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk
| Chemical Name: | 3-[[2-[3-(4-Morpholinylmethyl)phenyl]thieno[3,2-b]pyridin-7-yl]amino]phenol dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent PDGFRα and PDGFRβ inhibitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases
| Chemical Name: | N-(3-Fluorophenyl)-1,4-dihydro-6,7-dimethoxyindeno[1,2-c]pyrazol-3-amine |
| Purity: | ≥98% (HPLC) |
Negative control for PP 2 (Cat. No. 1407)
| Chemical Name: | 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% (HPLC) |
JAK2/STAT3 signaling pathway inhibitor
| Chemical Name: | (1R,5R,6R,7S)-rel-4-Oxo-8-(phenylmethyl)-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid 6,7-dimethyl ester |
| Purity: | ≥99% (HPLC) |
Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest
| Chemical Name: | 4-(2-Aminoethoxy)N2,N6-bis[(4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinecarboxamide pentahydrochloride |
| Purity: | ≥95% (HPLC) |
High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
| Chemical Name: | 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone |
| Purity: | ≥99% (HPLC) |
